Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | HTR1D | P28221 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13981216 | 0.81 | HTR1A (0.51) | HTR2CHTR1AHTR1DHTR2BSLC6A2 | |
| SCHEMBL7752945 | 0.81 | HTR1A (0.58) | HTR2CHTR1AHTR1DHTR2BSLC6A2 | |
| SCHEMBL172889 | 0.80 | HTR1A (0.57) | HTR2CHTR1AHTR1DHTR2BSIGMAR1 | |
| SCHEMBL8130244 | 0.80 | HTR1A (0.57) | HTR2CHTR1AHTR1D | |
| SCHEMBL30295621 | 0.80 | HTR1A (0.43) | HTR2CHTR1AHTR1DHTR2BSLC6A2 | |
| SCHEMBL6100632 | 0.80 | HTR1A (0.43) | HTR2CHTR1AHTR1DHTR2BSLC6A2 | |
| SCHEMBL6215060 | 0.77 | HTR1A (0.57) | HTR2CHTR1AHTR1DHCRTR2 | |
| SCHEMBL7757639 | 0.77 | HTR2C (0.53) | HTR2CHTR1AHTR1DSLC6A2HTR2A | |
| SCHEMBL27347333 | 0.76 | FFAR1 (0.60) | FFAR1PPARGPPARD | |
| SCHEMBL27347334 | 0.76 | FFAR1 (0.60) | FFAR1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059053-A1 | COMPOUNDS OF 2,3-DIHYDRO-BENZOFURAN | FERRER INTERNATIONAL, S.A. (ES) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059053-A1 | COMPOUNDS OF 2,3-DIHYDRO-BENZOFURAN | MTNR1A, MTNR1B, CRY2 | HTR2C 16/4885HTR1A 67/4885HTR1D 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.