Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752947 | 0.92 | HTR1A (0.56) | HTR2CHTR1AHTR1DTAAR1DRD2 | |
| SCHEMBL7752945 | 0.86 | HTR1A (0.58) | HTR2CHTR1AHTR1DTAAR1SLC6A2 | |
| SCHEMBL7757677 | 0.79 | MTNR1A (0.54) | HTR2CHTR1AHTR1D | |
| SCHEMBL95790 | 0.77 | HTR2C (0.61) | HTR2CHTR1AHTR1DHTR2ASLC6A2 | |
| SCHEMBL8130244 | 0.73 | HTR1A (0.57) | HTR2CHTR1AHTR1DTAAR1 | |
| SCHEMBL172889 | 0.73 | HTR1A (0.57) | HTR2CHTR1AHTR1DHTR2ADRD2 | |
| SCHEMBL8521537 | 0.73 | CTSD (0.41) | HTR2CSKP2HTR2ADRD2SLC6A2 | |
| SCHEMBL8575802 | 0.73 | CTSD (0.41) | HTR2CSKP2HTR2ADRD2SLC6A2 | |
| SCHEMBL11867423 | 0.72 | THRA (0.45) | HTR2CSLC6A2SLC6A4SPHK2SPHK1 | |
| SCHEMBL7755582 | 0.71 | MTNR1A (0.51) | HTR2CHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721947-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-14 | — | — | EP | disclosed |
| US-5703121-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-30 | — | — | US | disclosed |
| EP-0721947-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |