SCHEMBL958449

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10083334	0.82	MAOB (0.57)	KMT2ACYP4F2CYP4A11MAOB
	SCHEMBL7810973	0.77	AKR1C1 (0.55)	KMT2ACYP4F2CYP4A11MAOBAKR1C1
	SCHEMBL1009341	0.77	ALOX5 (0.47)	SLC22A12MAOB
	SCHEMBL1465003	0.77	KMT2A (0.50)	KMT2AAKR1C1
	SCHEMBL12658813	0.75	FFAR1 (0.42)	NR1H4SLC22A12MAOB
	SCHEMBL1007848	0.75	KMT2A (0.50)	KMT2ASLC22A12
	SCHEMBL11646688	0.75	TSHR (0.71)	KMT2ANR1H4AKR1C1
	SCHEMBL1633991	0.75	NR4A2 (0.65)	KMT2A
	SCHEMBL237290	0.75	MAOB (0.67)	KMT2ASLC22A12MAOB
	SCHEMBL31215373	0.75	NR4A2 (0.65)	KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.