Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | LOX | P28300 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3934050 | 0.85 | HTR6 (0.61) | HTR6LMNALOXLOXL2MAOA | |
| SCHEMBL13770797 | 0.83 | HTR6 (0.74) | HTR6LOXHTR2AHTR2CMAOA | |
| SCHEMBL1952494 | 0.83 | LMNA (0.68) | LMNALOXLOXL2MAOACA1 | |
| SCHEMBL9586629 | 0.83 | LOXL2 (0.50) | LMNALOXLOXL2CYP19A1MAOA | |
| SCHEMBL24917161 | 0.81 | HTR6 (0.77) | HTR6LOXHTR2AHTR2CMAOA | |
| SCHEMBL9589105 | 0.79 | L3MBTL1 (0.54) | LMNALOXLOXL2CYP19A1MAOA | |
| SCHEMBL9587487 | 0.79 | L3MBTL1 (0.50) | LMNALOXLOXL2CYP19A1MAOA | |
| SCHEMBL9646877 | 0.78 | SERPINE1 (0.56) | HTR6HTR2AHTR2CCA12CA1 | |
| SCHEMBL23169624 | 0.78 | ALDH1A1 (0.52) | LMNACYP19A1CA2TPSAB1CNR2 | |
| Bromide SCHEMBL9586294 | 0.78 | L3MBTL1 (0.53) | LMNALOXLOXL2CYP19A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013079-A1 | ANTIFOLATE QUINAZOLINES | AGOURON PHARMACEUTICALS, INC. (US) | 1993-07-08 | — | — | WO | disclosed |