Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | PARP16 | Q8N5Y8 | 2/20 | 0.31 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588575 | 1.00 | OPRM1 (0.32) | OPRM1OPRD1OPRK1OPRL1PARP16 | |
| SCHEMBL9588271 | 0.86 | DRD2 (0.34) | ABCC9DRD2DRD4 | |
| SCHEMBL9587643 | 0.83 | ALDH1A1 (0.32) | — | |
| SCHEMBL9702059 | 0.83 | ALDH1A1 (0.32) | — | |
| SCHEMBL9588012 | 0.81 | IDO1 (0.34) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9589616 | 0.81 | MAPK1 (0.36) | OPRM1OPRD1 | |
| SCHEMBL9589012 | 0.81 | ALDH1A1 (0.36) | — | |
| SCHEMBL9587842 | 0.80 | MEN1 (0.41) | — | |
| SCHEMBL9701823 | 0.80 | MEN1 (0.41) | — | |
| SCHEMBL9588026 | 0.79 | ABCC9 (0.40) | ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489300-A2 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1992-06-10 | — | — | EP | disclosed |