Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587842 | 1.00 | MEN1 (0.41) | MEN1GAAKMT2AMAPTCA1 | |
| SCHEMBL9589012 | 0.83 | ALDH1A1 (0.36) | MEN1GAAKMT2ACA1CA2 | |
| SCHEMBL9588012 | 0.83 | IDO1 (0.34) | MAPTCA1CA2CA7CA9 | |
| SCHEMBL9588271 | 0.83 | DRD2 (0.34) | MEN1KMT2AMAPTPDK2ALDH1A1 | |
| SCHEMBL9587643 | 0.82 | ALDH1A1 (0.32) | MEN1KMT2AMAPTCA1CA2 | |
| SCHEMBL9702059 | 0.82 | ALDH1A1 (0.32) | MEN1KMT2AMAPTCA1CA2 | |
| SCHEMBL9588559 | 0.81 | HSD17B1 (0.34) | MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9588026 | 0.81 | ABCC9 (0.40) | PDK2 | |
| SCHEMBL9703970 | 0.81 | ABCC9 (0.40) | PDK2 | |
| SCHEMBL9588575 | 0.80 | OPRM1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489300-A2 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1992-06-10 | — | — | EP | disclosed |