Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 2/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702059 | 1.00 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL9588012 | 0.84 | IDO1 (0.34) | MAPTMAPK1IDO1TDO2CA1 | |
| SCHEMBL9588271 | 0.84 | DRD2 (0.34) | ALDH1A1MEN1KMT2AMAPTATM | |
| SCHEMBL9589616 | 0.84 | MAPK1 (0.36) | ALDH1A1TSHRMAPK1L3MBTL1POLB | |
| SCHEMBL9589012 | 0.84 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL9703085 | 0.83 | OPRM1 (0.32) | — | |
| SCHEMBL9588575 | 0.83 | OPRM1 (0.32) | — | |
| SCHEMBL9587842 | 0.82 | MEN1 (0.41) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL9701823 | 0.82 | MEN1 (0.41) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL9588559 | 0.81 | HSD17B1 (0.34) | MEN1KMT2AMAPTKDM4EAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5272170-A | Tetralones with pharmacological activity | J. URIACH & CIA., S.A. (ES) | 1993-12-21 | — | — | US | disclosed |
| US-5208246-A | Hypotensive, bronchodilator | J. URIACH & CIA. (ES) | 1993-05-04 | — | — | US | disclosed |