Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9603010 | 0.88 | PDE4A (0.34) | ABCB1MAPTPDE4APDE4BPDE4C | |
| SCHEMBL9596467 | 0.88 | ALDH1A1 (0.36) | ABCC9ABCB1MAPTPDE4APDE4B | |
| SCHEMBL9682834 | 0.75 | PDPK1 (0.39) | ABCC9ABCB1PDE4APDE4BPDE4C | |
| SCHEMBL9527648 | 0.73 | ABCC9 (0.39) | ABCC9NPC1MAPTPKMPDE4A | |
| SCHEMBL9590268 | 0.73 | ABCC9 (0.49) | ABCC9ABCB1MEN1KMT2A | |
| SCHEMBL9827460 | 0.72 | ABCC9 (0.40) | ABCC9MAOAMAOBNPC1MAPT | |
| SCHEMBL9682845 | 0.71 | PDGFRB (0.41) | POLBMAPTMEN1KMT2ADAO | |
| SCHEMBL8642468 | 0.70 | PDE4A (0.38) | ABCC9ABCB1PDE4APDE4BPDE4C | |
| SCHEMBL7266970 | 0.69 | ABCC9 (0.41) | ABCC9ABCB1PDE4APDE4BPDE4C | |
| SCHEMBL8643067 | 0.69 | PDE4A (0.35) | ABCC9ABCB1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189047-A | Useful in the treament of respiratory track disorder, hypertension and bronchodilator activity or utility as potassium channel activator | BEECHAM GROUP P.L.C. (GB) | 1993-02-23 | — | — | US | disclosed |
| EP-0413438-A1 | Benzopyran compounds | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | disclosed |