SCHEMBL9602940

SCHEMBL9602940

O=C(Cl)c1ccc(S(=O)(=O)c2ccc3c(c2)C(=O)OC3=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
POLB P06746 4/20 0.43
TSHR P16473 2/20 0.42
GAA P10253 2/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CA12 O43570 4/20 0.39
CA7 P43166 4/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CA4 P22748 2/20 0.38
MAPT P10636 3/20 0.36
MCL1 Q07820 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TP53 P04637 1/20 0.35
THRB P10828 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL209746 0.83 ALDH1A1 (0.50) ALDH1A1POLBTSHRGAAATM
SCHEMBL29357601 0.83 ALDH1A1 (0.50) ALDH1A1POLBTSHRGAAATM
SCHEMBL4959613 0.80 HTR6 (0.52) ALDH1A1POLBTSHRL3MBTL1MAPT
SCHEMBL74379 0.80 CA12 (0.49) ALDH1A1POLBTSHRCA12CA7
SCHEMBL29490657 0.80 CA12 (0.49) ALDH1A1POLBTSHRCA12CA7
SCHEMBL724893 0.78 ALDH1A1 (0.50) ALDH1A1POLBTSHRGAAL3MBTL1
SCHEMBL9516335 0.78 F2 (0.49) ALDH1A1POLBTSHRGAAATM
SCHEMBL23630427 0.78 CA12 (0.42) ALDH1A1ATML3MBTL1CA12CA7
SCHEMBL29868120 0.78 CA12 (0.42) ALDH1A1ATML3MBTL1CA12CA7
SCHEMBL9602971 0.78 CA12 (0.45) ALDH1A1TSHRATML3MBTL1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0315992-B1 SULFUR-CONTAINING AROMATIC TETRACARBOXYLIC ACIDS AND THEIR DERIVATIVES CHEMIE LINZ GMBH (AT) 1993-08-11 EP disclosed
EP-0315993-B1 SOLUBLE AND/OR FUSIBLE BLOCK POLYAMIDE-POLYAMIDES, POLYAMIDE-POLYAMIDEIMIDES AND POLYAMIDES-POLYIMIDES Chemie Linz Gesellschaft m.b.H. (AT) 1992-04-01 EP disclosed
EP-0390803-A1 SULFUR-CONTAINING AROMATIC TETRACARBOXYLIC ACIDS AND THEIR DERIVATIVES Chemie Linz Gesellschaft m.b.H. (AT) 1990-10-10 EP disclosed
WO-1989004298-A1 SULFUR-CONTAINING AROMATIC TETRACARBOXYLIC ACIDS AND THEIR DERIVATIVES CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1989-05-18 WO disclosed
EP-0315992-A1 Sulfur-containing aromatic tetracarboxylic acids and their derivatives Chemie Linz Gesellschaft m.b.H. (AT) 1989-05-17 EP disclosed
EP-0315993-A1 Soluble and/or fusible block polyamide-polyamides, polyamide-polyamideimides and polyamides-polyimides Chemie Linz Gesellschaft m.b.H. (AT) 1989-05-17 EP disclosed