Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9603688 | 0.84 | MAPT (0.47) | RAB9AALDH1A1MAPTKDM4ENPSR1 | |
| SCHEMBL9599417 | 0.69 | KDM4E (0.57) | RAB9ANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL9603759 | 0.68 | GABRP (0.41) | RAB9ANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL9598196 | 0.68 | ADORA1 (0.43) | NPC1ALDH1A1MAPTKDM4EHTT | |
| SCHEMBL9597904 | 0.67 | BPTF (0.46) | ALDH1A1MAPTKDM4EHTTADORA1 | |
| SCHEMBL2662077 | 0.65 | ALDH1A1 (0.50) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9598034 | 0.65 | PRKCI (0.48) | RAB9ANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL4419311 | 0.64 | RAB9A (0.74) | RAB9ANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL17307669 | 0.64 | MKNK1 (0.48) | LIMK1P2RX3 | |
| SCHEMBL9598331 | 0.63 | ADORA1 (0.64) | MAPTKDM4EADORA1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013104-A1 | C.N.S. ACTIVE TRICYCLIC THIENOPYRIDINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1993-07-08 | — | — | WO | disclosed |