Sugi Predict

Sugi Predict / Compounds / SCHEMBL960732

SCHEMBL960732

SCHEMBL960732

OB(O)Oc1ccccc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.44
▸ L3MBTL1 Q9Y468 2/20 0.44
▸ MAPK1 P28482 2/20 0.44
▸ TP53 P04637 1/20 0.44
▸ RAB9A P51151 1/20 0.44
▸ NCOA1 Q15788 1/20 0.44
▸ NCOA3 Q9Y6Q9 1/20 0.44
▸ ALDH1A1 P00352 2/20 0.43
▸ HPGD P15428 1/20 0.43
▸ BCL2L1 Q07817 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ HRH1 P35367 1/20 0.42
▸ HTR7 P34969 1/20 0.42
▸ LMNA P02545 3/20 0.41
▸ RXRA P19793 1/20 0.41
▸ RXRB P28702 1/20 0.41
▸ RXRG P48443 1/20 0.41
▸ KDM4E B2RXH2 3/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ FABP7 O15540 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30725510 1.00 TDP1 (0.44) TDP1L3MBTL1MAPK1TP53RAB9A
SCHEMBL31657742 0.86 ENPP2 (0.39) TP53ALDH1A1HTR7LMNA
SCHEMBL2420028 0.86 SLC6A4 (0.45) ALDH1A1HTR7LMNA
SCHEMBL2413434 0.84 SYK (0.46) TDP1L3MBTL1MAPK1RAB9AALDH1A1
SCHEMBL21809381 0.84 ADRA2A (0.41) MAPK1TP53RAB9AALDH1A1HSD17B10
SCHEMBL5377023 0.84 SLC6A4 (0.44) TP53RAB9AALDH1A1HPGDHSD17B10
SCHEMBL31104880 0.83 ERN1 (0.38) TDP1L3MBTL1MAPK1TP53RAB9A
SCHEMBL4175974 0.82 MAPK1 (0.47) TDP1L3MBTL1MAPK1TP53RAB9A
SCHEMBL30789177 0.81 FFAR4 (0.39) BACE1
SCHEMBL31474145 0.81 L3MBTL1 (0.38) TDP1L3MBTL1MAPK1TP53RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105693608-A 2, 2-dimethyl-1, 3-indene dione derivatives and organic electroluminescent devices based thereon 中国科学院理化技术研究所 2016-06-22 — — CN claimed
CN-114957251-B High-performance photoelectric material, preparation method and organic electroluminescent device 烟台九目化学股份有限公司 2024-03-15 — — CN disclosed
CN-116375659-A Organic compound, and electronic component and electronic device including the same 陕西莱特光电材料股份有限公司 2023-07-04 — — CN disclosed
US-10987349-B2 Antitumor agent and bromodomain inhibitor FUJIFILM CORPORATION (JP) 2021-04-27 — — US disclosed
EP-3563851-B1 ANTITUMOR AGENT AND BROMODOMAIN INHIBITOR FUJIFILM CORP (JP) 2021-04-21 — — EP disclosed
EP-3327004-B1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND FUJIFILM CORP (JP) 2020-11-04 — — EP disclosed
US-10696637-B2 Nitrogen-containing heterocyclic compound FUJIFILM CORPORATION (JP) 2020-06-30 — — US disclosed
US-10633343-B2 — — 2020-04-28 — — US disclosed
EP-3563851-A1 ANTITUMOR AGENT AND BROMODOMAIN INHIBITOR FUJIFILM Corporation (JP) 2019-11-06 — — EP disclosed
US-20190314360-A1 ANTITUMOR AGENT AND BROMODOMAIN INHIBITOR FUJIFILM CORPORATION (JP) 2019-10-17 — — US disclosed
US-20120298980-A1 ORGANIC ELECTROLUMINESCENT DEVICE UDC IRELAND LIMITED (IE) 2012-11-29 — — US disclosed
US-8273467-B2 Organic electroluminescent device FUJIFILM CORPORATION (JP) 2012-09-25 — — US disclosed
US-8026370-B2 Peroxisome proliferator antagonist; hyperlipemia agents; arteriosclerosis; antiischemic agents MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-09-27 — — US disclosed
US-20110001864-A1 ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2011-01-06 — — US disclosed
WO-2009139501-A1 ORGANIC LIGHT EMITTING DEVICE, IMAGE DISPLAY APPARATUS, CAMERA CANON KABUSHIKI KAISHA (JP) 2009-11-19 — — WO disclosed
US-20080167307-A1 Carboxylic Acid Derivative Containing Thiazole Ring and Pharmaceutical Use Thereof MITSUBISHI PHAMA CORPORATION (JP) 2008-07-10 — — US disclosed
US-20070202358-A1 Organic electroluminescent device FUJIFILM CORPORATION (JP) 2007-08-30 — — US disclosed
EP-1816128-A1 CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF Mitsubishi Pharma Corporation (JP) 2007-08-08 — — EP disclosed
US-20070122652-A1 Compound and organic electroluminescent device using same CANON KABUSHIKI KAISHA (JP) 2007-05-31 — — US disclosed
WO-2006035997-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2006-04-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080167307-A1 Carboxylic Acid Derivative Containing Thiazole Ring and Pharmaceutical Use Thereof PPARA, PPARD, PPARG TDP1 4316/4885L3MBTL1 4700/4885MAPK1 2750/4885
US-10987349-B2 Antitumor agent and bromodomain inhibitor BRD4, BRD1, BRD3 TDP1 2957/4885L3MBTL1 209/4885MAPK1 1104/4885
US-10696637-B2 Nitrogen-containing heterocyclic compound CXCL10, CCL5, CXCR3 TDP1 2669/4885L3MBTL1 1195/4885MAPK1 994/4885
US-20070122652-A1 Compound and organic electroluminescent device using same OR10J3, LEF1, RPL19 TDP1 3218/4885L3MBTL1 163/4885MAPK1 942/4885
US-20190314360-A1 ANTITUMOR AGENT AND BROMODOMAIN INHIBITOR BRD4, BRD1, BRD3 TDP1 2957/4885L3MBTL1 209/4885MAPK1 1104/4885
US-10633343-B2 — CXCL10, CCL5, CXCR3 TDP1 2830/4885L3MBTL1 770/4885MAPK1 1360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.