Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8880685 | 0.78 | ALDH1A1 (0.32) | ALDH1A1TSHRRIPK1DRD4OPRM1 | |
| SCHEMBL2740778 | 0.78 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL19608819 | 0.77 | RIPK1 (0.39) | RIPK1 | |
| SCHEMBL11621506 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TSHRDRD4OPRM1DRD3 | |
| SCHEMBL5264333 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TSHRRIPK1DRD4OPRM1 | |
| SCHEMBL20857549 | 0.76 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| SCHEMBL12293705 | 0.76 | ALDH1A1 (0.30) | ALDH1A1TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11809225 | 0.76 | KDM4E (0.36) | ALDH1A1TSHR | |
| SCHEMBL23370118 | 0.75 | AOC2 (0.35) | — | |
| SCHEMBL1712705 | 0.75 | MAPT (0.42) | RIPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230540-A2 | INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023230543-A1 | INDOLIZINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023230542-A2 | PYRAZOLO[1,5-a]PYRIDINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| EP-2462104-B1 | METHOD FOR SYNTHESIZING AMINOALCOHOLS | LUBRIZOL ADVANCED MAT INC (US) | 2016-11-23 | — | — | EP | disclosed |
| US-8766011-B2 | Method for synthesizing aminoalcohols | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-20120136174-A1 | Method For Synthesizing Aminoalcohols | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2012-05-31 | — | — | US | disclosed |
| WO-2011017510-A2 | METHOD FOR SYNTHESIZING AMINOALCOHOLS | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136174-A1 | Method For Synthesizing Aminoalcohols | THEM6, AADAT, INF2 | ALDH1A1 366/4885TSHR 4696/4885RIPK1 1987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.