Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21663870 | 0.69 | MAPT (0.48) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL5777989 | 0.68 | ALDH1A1 (0.43) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL8378973 | 0.68 | MGLL (0.43) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL21664123 | 0.68 | ALDH1A1 (0.47) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL10231621 | 0.67 | LMNA (0.41) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL518175 | 0.67 | LMNA (0.41) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL21664141 | 0.65 | LMNA (0.34) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL6911993 | 0.65 | NOS3 (0.31) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL6170485 | 0.64 | CYP2A6 (0.50) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL18624160 | 0.63 | CYP2A6 (0.43) | LMNASMN1; SMN2ALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106316914-A | Method for preparing 3-alkenylpyrrole derivatives | 中国科学院大连化学物理研究所 | 2017-01-11 | — | — | CN | claimed |
| CN-106316914-A | Method for preparing 3-alkenylpyrrole derivatives | 中国科学院大连化学物理研究所 | 2017-01-11 | — | — | CN | disclosed |