Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420392 | 0.86 | TRPA1 (0.48) | MAPK1TRPA1 | |
| SCHEMBL9613974 | 0.86 | TRPA1 (0.48) | MAPK1TRPA1 | |
| SCHEMBL9858293 | 0.86 | FFAR1 (0.47) | MEN1KMT2A | |
| SCHEMBL9614317 | 0.84 | MMP3 (0.52) | ALDH1A1MEN1KMT2AMMP1MMP2 | |
| SCHEMBL9614190 | 0.84 | MMP3 (0.52) | ALDH1A1MEN1KMT2AMMP1MMP2 | |
| SCHEMBL9614242 | 0.82 | TDP1 (0.43) | ALDH1A1TRPA1 | |
| SCHEMBL9614055 | 0.81 | TRPA1 (0.48) | MAPK1TRPA1 | |
| SCHEMBL9858299 | 0.81 | PPARG (0.50) | ALDH1A1MMP1MMP3 | |
| SCHEMBL9857963 | 0.80 | ALDH1A1 (0.44) | LMNAALDH1A1NPC1TRPA1 | |
| SCHEMBL9614112 | 0.80 | PPARA (0.48) | ALDH1A1MEN1KMT2AMMP2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |