Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.53 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9617454 | 1.00 | TSHR (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Crotonic Acid SCHEMBL3409852 | 0.87 | TSHR (0.38) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Crotonic Acid SCHEMBL3409845 | 0.87 | TSHR (0.38) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Maleic Acid SCHEMBL16506278 | 0.86 | TSHR (0.50) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Fumaric Acid SCHEMBL16506280 | 0.86 | TSHR (0.50) | TSHRTP53EGLN1EGLN3HCAR2 | |
| (2E)-Hexenoic Acid SCHEMBL3414440 | 0.83 | TAS1R3 (0.41) | TSHRTP53EGLN1EGLN3HCAR2 | |
| (2E)-Hexenoic Acid SCHEMBL3414436 | 0.83 | TAS1R3 (0.41) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Fumaric Acid SCHEMBL5152411 | 0.82 | ALDH1A1 (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Fumaric Acid SCHEMBL2350872 | 0.82 | ALDH1A1 (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Maleic Acid SCHEMBL2350870 | 0.82 | ALDH1A1 (0.53) | TSHRTP53EGLN1EGLN3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4037111-A | — | — | None | — | — | JP | disclosed |
| US-20250174409-A1 | SOLID ELECTROLYTE CAPACITOR AND METHOD FOR MANUFACTURING SAME | CARLIT CO., LTD. (JP) | 2025-05-29 | — | — | US | disclosed |
| CN-118843914-A | Solid electrolytic capacitor and method for manufacturing the same | 佳里多股份公司 | 2024-10-25 | — | — | CN | disclosed |
| WO-2023171344-A1 | SOLID ELECTROLYTE CAPACITOR AND METHOD FOR MANUFACTURING SAME | カーリットホールディングス株式会社 | 2023-09-14 | — | — | WO | disclosed |
| EP-2975620-B1 | ALUMINUM ELECTROLYTIC CAPACITOR-USE ELECTROLYTIC SOLUTION AND ALUMINUM ELECTROLYTIC CAPACITOR USING SAME | SANYO CHEMICAL IND LTD (JP) | 2019-05-22 | — | — | EP | disclosed |
| EP-2843673-B1 | ELECTROLYTIC SOLUTION FOR ALUMINUM ELECTROLYTIC CAPACITOR, AND ALUMINUM ELECTROLYTIC CAPACITOR USING SAME | SANYO CHEMICAL IND LTD (JP) | 2019-01-16 | — | — | EP | disclosed |
| US-9959977-B2 | Electrolysis solution for electrolytic capacitor, and electrolytic capacitor | CARLIT HOLDINGS CO., LTD. (JP) | 2018-05-01 | — | — | US | disclosed |
| US-9793059-B2 | Electrolytic solution for aluminum electrolytic capacitor and aluminum electrolytic capacitor using the same | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2017-10-17 | — | — | US | disclosed |
| US-9691552-B2 | Electrolytic solution for aluminum electrolytic capacitor, and aluminum electrolytic capacitor using same | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2017-06-27 | — | — | US | disclosed |
| US-20160148756-A1 | ELECTROLYSIS SOLUTION FOR ELECTROLYTIC CAPACITOR, AND ELECTROLYTIC CAPACITOR | CARLIT CO., LTD. (JP) | 2016-05-26 | — | — | US | disclosed |
| CN-105340034-A | Electrolysis solution for electrolytic capacitor, and electrolytic capacitor | CARLIT HOLDINGS CO LTD | 2016-02-17 | — | — | CN | disclosed |
| US-20160020036-A1 | ELECTROLYTIC SOLUTION FOR ALUMINUM ELECTROLYTIC CAPACITOR AND ALUMINUM ELECTROLYTIC CAPACITOR USING THE SAME | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2016-01-21 | — | — | US | disclosed |
| EP-2975620-A1 | ALUMINUM ELECTROLYTIC CAPACITOR-USE ELECTROLYTIC SOLUTION AND ALUMINUM ELECTROLYTIC CAPACITOR USING SAME | Sanyo Chemical Industries, Ltd. (JP) | 2016-01-20 | — | — | EP | disclosed |
| EP-2843673-A1 | ELECTROLYTIC SOLUTION FOR ALUMINUM ELECTROLYTIC CAPACITOR, AND ALUMINUM ELECTROLYTIC CAPACITOR USING SAME | Sanyo Chemical Industries, Ltd. (JP) | 2015-03-04 | — | — | EP | disclosed |
| US-20150053882-A1 | ELECTROLYTIC SOLUTION FOR ALUMINUM ELECTROLYTIC CAPACITOR, AND ALUMINUM ELECTROLYTIC CAPACITOR USING SAME | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2015-02-26 | — | — | US | disclosed |
| CN-104115245-A | Electrolytic solution for aluminum electrolytic capacitor, and aluminum electrolytic capacitor using same | SANYO CHEMICAL IND LTD | 2014-10-22 | — | — | CN | disclosed |
| JP-H0437111-A | ELECTROLYTE FOR ELECTROLYTIC CAPACITOR | ELNA CO LTD | 1992-02-07 | — | — | JP | disclosed |