Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10530855 | 0.83 | ALDH1A1 (0.42) | CA2CA4CA5AESR1LMNA | |
| SCHEMBL9617518 | 0.79 | CA2 (0.52) | CA2CA4CA5AESR1LMNA | |
| SCHEMBL22873312 | 0.75 | HPGD (0.31) | LMNATSHR | |
| SCHEMBL10534669 | 0.75 | CA12 (0.40) | CA2CA4CA5ALMNAALDH1A1 | |
| SCHEMBL10534613 | 0.73 | LMNA (0.52) | CA2CA4CA5ALMNAALDH1A1 | |
| SCHEMBL13043277 | 0.72 | KDM4E (0.48) | CA2CA4CA5ALMNAALDH1A1 | |
| SCHEMBL15256343 | 0.72 | TSHR (0.47) | CA2CA4CA5AESR1LMNA | |
| SCHEMBL115791 | 0.71 | ESR1 (0.71) | CA2CA4CA5AESR1ALDH1A1 | |
| SCHEMBL25435946 | 0.69 | ESR1 (0.68) | CA2CA4CA5AESR1ALDH1A1 | |
| SCHEMBL31247 | 0.69 | ESR1 (0.54) | CA2CA4CA5AESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829044-B2 | Phosphonamides, process for producing the same, and use thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-11-09 | — | — | US | disclosed |
| US-6924396-B2 | α-haloenamine reagents | PHARMACIA CORPORATION (US) | 2005-08-02 | — | — | US | disclosed |
| EP-1421056-A1 | (ALPHA)-HALOENAMINE REAGENTS | Pharmacia Corporation (US) | 2004-05-26 | — | — | EP | disclosed |
| US-20040092770-A1 | Alpha-haloenamine reagents | PHARMACIA CORPORATION | 2004-05-13 | — | — | US | disclosed |
| US-6677487-B2 | COMBINING A TERTIARY AMIDE WITH A PENTAVALENT PHOSPHOROUS HALIDE IN A SOLVENT TO FORM AN ALPHA - HALOIMINIUM SALT AND CONVERTING THE ALPHA -HALOIMINIUM SALT TO THE ALPHA -HALOENAMINE WITH A BASE | PHARMACIA CORPORATION | 2004-01-13 | — | — | US | disclosed |
| US-20030080320-A1 | Alpha- haloenamine reagents | PHARMACIA CORPORATION | 2003-05-01 | — | — | US | disclosed |
| WO-2003020684-A1 | (ALPHA)-HALOENAMINE REAGENTS | PHARMACIA CORPORATION (US) | 2003-03-13 | — | — | WO | disclosed |
| US-4804655-A | Pesticidal cyclic malonylphosphonic diamides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| US-4739090-A | REACTING PHOSPHOROUS TRICHLORIDE, PENTAERYTHRITOL, AND ALKYL PHENOL IN PRESENCE OF CATALYST | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4492661-A | Process for producing triarylphosphites | CIBA-GEIGY CORPORATION (US) | 1985-01-08 | — | — | US | disclosed |
| US-4440696-A | FROM A PHENOL AND PHOSPHORUS TRIHALIDE, AMINE OR AMIDE CATALYST | CIBA-GEIGY CORPORATION (US) | 1984-04-03 | — | — | US | disclosed |
| US-4312818-A | CATALYZED REACTION OF A PHENOL WITH A PHOSPHORUS HALIDE | CIBA-GEIGY CORPORATION (US) | 1982-01-26 | — | — | US | disclosed |
| EP-0000757-B1 | PROCESS FOR THE PREPARATION OF TRIARYLPHOSPHITES | CIBA-GEIGY AG (CH) | 1981-08-05 | — | — | EP | disclosed |
| US-4251469-A | ADDITIVES FOR EXTREME PRESSURE LUBRICANTS | CIBA-GEIGY CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
| US-4197209-A | Lubricant compositions containing sulfur-containing esters of phosphoric acid | CIBA-GEIGY CORPORATION (US) | 1980-04-08 | — | — | US | disclosed |
| US-4189453-A | FROM MERCAPTANS AND PHOSPHORUS TRIHALIDE, CATALYTIC | CIBA-GEIGY CORPORATION (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0000757-A1 | Process for the preparation of triarylphosphites | CIBA-GEIGY AG (CH) | 1979-02-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030080320-A1 | Alpha- haloenamine reagents | HNMT, HDHD5, NISCH | CA2 943/4885CA4 985/4885CA5A 2308/4885 |
| US-20040092770-A1 | Alpha-haloenamine reagents | HNMT, HDHD5, NISCH | CA2 943/4885CA4 985/4885CA5A 2308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.