Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRYAB | P02511 | 5/20 | 0.46 |
| ▸ | CRYAA | P02489 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 2/20 | 0.46 |
| ▸ | ACACA | Q13085 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.42 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 2/20 | 0.38 |
| ▸ | VDR | P11473 | 4/20 | 0.36 |
| ▸ | OSBP | P22059 | 1/20 | 0.36 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599781 | 0.87 | HSD11B1 (0.56) | ACLYACACAHSD11B1HSD11B2PTPN11 | |
| SCHEMBL1878450 | 0.87 | HSD11B1 (0.56) | ACLYACACAHSD11B1HSD11B2PTPN11 | |
| SCHEMBL1874653 | 0.84 | ACLY (0.48) | ACLYACACAHSD11B1HSD11B2PTPN11 | |
| SCHEMBL16411312 | 0.82 | ACLY (0.61) | CRYABACLYACACAHSD11B1HSD11B2 | |
| SCHEMBL568813 | 0.81 | HSD11B1 (0.50) | ACLYACACAHSD11B1HSD11B2PTPN11 | |
| SCHEMBL8148952 | 0.73 | EBP (0.48) | ACLYACACAHSD11B1PTPN11EBP | |
| Cycloartanol SCHEMBL13801860 | 0.72 | ACLY (0.67) | CRYABCRYAAACLYACACAHSD11B1 | |
| Cycloartanol SCHEMBL12152356 | 0.72 | ACLY (0.67) | CRYABCRYAAACLYACACAHSD11B1 | |
| Cycloartanol SCHEMBL1881616 | 0.72 | ACLY (0.67) | CRYABCRYAAACLYACACAHSD11B1 | |
| Cycloartanol SCHEMBL1881613 | 0.72 | ACLY (0.67) | CRYABCRYAAACLYACACAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2032022-A | — | — | None | — | — | JP | disclosed |
| JP-4082833-A | — | — | None | — | — | JP | disclosed |
| JP-H0482833-A | LIPID MICROSPHERE PREPARATION CONTAINING STEROID COMPOUND | SAITO SHOJI | 1992-03-16 | — | — | JP | disclosed |
| JP-H0232022-A | CEREBRAL FUNCTION ACTIVATOR CONTAINING STEROID COMPOUND | SAITO SHOJI | 1990-02-01 | — | — | JP | disclosed |