Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849527 | 0.84 | ALDH1A1 (0.44) | RAB9AKDM4EALDH1A1SMYD3KMT2A | |
| SCHEMBL9849537 | 0.73 | KMT2A (0.46) | RAB9AALDH1A1SMYD3KMT2AMEN1 | |
| SCHEMBL9618669 | 0.73 | MAPT (0.44) | SMYD3SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL16083181 | 0.72 | HPGD (0.69) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13797489 | 0.71 | TRPV4 (0.48) | ALDH1A1KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL2372258 | 0.69 | HDAC8 (0.57) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL27183053 | 0.69 | ITGA1 (0.41) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL4768355 | 0.69 | RAB9A (0.46) | RAB9ACYP2C9CYP2C19CA12CA1 | |
| SCHEMBL17656862 | 0.68 | HPGD (0.62) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3454836 | 0.68 | HPGD (0.66) | RAB9AKDM4EALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454459-A2 | Sulfonylalkanoic acid amide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1991-10-30 | — | — | EP | claimed |
| EP-0454459-A2 | Sulfonylalkanoic acid amide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1991-10-30 | — | — | EP | disclosed |