SCHEMBL9619955

SCHEMBL9619955

COC(=O)C(OC(=O)Nc1cc(OC(C)C)c(Cl)cc1F)C1CCCC1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPOX P50336 4/20 0.42
TSHR P16473 2/20 0.39
SLC6A3 Q01959 2/20 0.38
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
NPSR1 Q6W5P4 3/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
STAT3 P40763 1/20 0.36
RORC P51449 1/20 0.36
DHODH Q02127 4/20 0.35
GAA P10253 1/20 0.35
MAPK1 P28482 1/20 0.35
LMNA P02545 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TP53 P04637 1/20 0.34
P2RX3 P56373 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9836339 0.80 DHODH (0.40) TSHRNPSR1ALDH1A1MAPTRORC
SCHEMBL27368859 0.79 RORC (0.40) PPOXNPSR1ALDH1A1MAPTHPGD
SCHEMBL9835444 0.79 RORC (0.39) PPOXTSHRNPSR1ALDH1A1KDM4E
SCHEMBL9867058 0.77 PPOX (0.37) PPOXNPSR1MAPTRORCDHODH
SCHEMBL10576902 0.76 P2RX3 (0.46) PPOXTSHRNPSR1ALDH1A1KDM4E
SCHEMBL9837732 0.75 SMN1; SMN2 (0.43) NPSR1ALDH1A1KDM4EMAPTHPGD
SCHEMBL9620110 0.74 GAA (0.41) PPOXTSHRNPSR1ALDH1A1MAPT
SCHEMBL9836594 0.74 RORC (0.47) PPOXNPSR1ALDH1A1KDM4EMAPT
SCHEMBL8895253 0.74 PPOX (0.42) PPOXTSHRDHODHL3MBTL1
SCHEMBL9769699 0.73 PPOX (0.46) PPOXTSHRTAS1R3TAS1R1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100457-A OXAZOLIDINEDIONE COMPOUNDS, THE PROCESS FOR PREPARING THE SAME AND HERBICIDAL COMPOSITION CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-03-31 US disclosed
EP-0382884-A1 Oxazolidinedione compounds, the process for preparing the same and herbicidal composition containing the same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1990-08-22 EP disclosed