Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344658 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4EKCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL9835444 | 0.87 | RORC (0.39) | KDM4EKCNQ3KCNQ2ALDH1A1HPGD | |
| SCHEMBL9836339 | 0.82 | DHODH (0.40) | KCNQ3KCNQ2ALDH1A1RORCDHODH | |
| SCHEMBL9836714 | 0.81 | LMNA (0.41) | SMN1; SMN2ALDH1A1HPGDRORCDHODH | |
| SCHEMBL9836348 | 0.77 | RORC (0.37) | SMN1; SMN2KCNQ3KCNQ2ALDH1A1HPGD | |
| SCHEMBL9835450 | 0.77 | NPSR1 (0.43) | SMN1; SMN2KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL27314992 | 0.77 | DHODH (0.37) | SMN1; SMN2KCNQ3KCNQ2HPGDRORC | |
| SCHEMBL9835245 | 0.76 | MEN1 (0.46) | SMN1; SMN2KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL8998058 | 0.75 | LMNA (0.34) | SMN1; SMN2KDM4EALDH1A1HPGDRORC | |
| SCHEMBL9619955 | 0.75 | PPOX (0.42) | KDM4EALDH1A1HPGDRORCDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241559-B1 | OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4983751-A | Chemical intermediates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-08 | — | — | US | disclosed |