Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 3/20 | 0.41 |
| ▸ | GRM6 | O15303 | 3/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050834 | 0.85 | MAPT (0.44) | ESR1SMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL4683206 | 0.83 | MAPT (0.52) | SMN1; SMN2NPC1HPGDRAB9AL3MBTL1 | |
| SCHEMBL7050830 | 0.81 | ALDH1A1 (0.57) | ALDH1A1FOLH1 | |
| SCHEMBL11262003 | 0.80 | GRM4 (0.41) | SMN1; SMN2HPGDL3MBTL1ALDH1A1GRM8 | |
| SCHEMBL1553456 | 0.79 | FOLH1 (0.51) | ESR1SMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL1461981 | 0.76 | ATM (0.60) | SMN1; SMN2NPC1HPGDRAB9AL3MBTL1 | |
| SCHEMBL11491274 | 0.76 | ATM (0.60) | SMN1; SMN2NPC1HPGDRAB9AL3MBTL1 | |
| SCHEMBL4685821 | 0.75 | ATM (0.63) | SMN1; SMN2NPC1HPGDRAB9AL3MBTL1 | |
| SCHEMBL5226412 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1HPGDRAB9AL3MBTL1 | |
| SCHEMBL4686341 | 0.74 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1HPGDRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |