Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620871 | 0.90 | DYRK1A (0.53) | DYRK1ADUSP3KDM4EMAPTKMT2A | |
| SCHEMBL9620801 | 0.89 | LMNA (0.51) | DYRK1ADUSP3KDM4EMAPTKMT2A | |
| SCHEMBL9620668 | 0.86 | APP (0.64) | DYRK1AKDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL9620827 | 0.81 | KDM4E (0.61) | DYRK1ADUSP3KDM4EMAPTKMT2A | |
| SCHEMBL9620754 | 0.81 | ALDH1A1 (0.56) | DYRK1ADUSP3KDM4EMAPTKMT2A | |
| SCHEMBL13806222 | 0.81 | ALDH1A1 (0.56) | DYRK1ADUSP3KDM4EMAPTKMT2A | |
| SCHEMBL143850 | 0.81 | ALDH1A1 (0.59) | DYRK1ADUSP3KDM4EMAPTKMT2A | |
| SCHEMBL1983852 | 0.80 | CYP3A4 (0.63) | DYRK1AKDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL1040735 | 0.79 | DYRK1A (0.63) | DYRK1ADUSP3KDM4EMAPTKMT2A | |
| SCHEMBL3374002 | 0.79 | RAB9A (0.63) | KDM4EMAPTKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306708-B1 | NOVEL BENZOTHIAZOLE AND ANTIRHEUMATIC AGENT COMPRISING IT AS AN ACTIVE INGREDIENT | KANEBO, LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4910211-A | Containing a phenyl substituted in position 2 and an ester in position 4 | KANEBO LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0306708-A1 | Novel benzothiazole and antirheumatic agent comprising it as an active ingredient | KANEBO, LTD. (JP) | 1989-03-15 | — | — | EP | disclosed |