Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.50 |
| ▸ | RELA | Q04206 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.48 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620877 | 0.90 | CA2 (0.56) | SMN1; SMN2MAPTTP53NPC1RAB9A | |
| SCHEMBL6219017 | 0.85 | HDAC6 (0.48) | MAPTHDAC6NPC1DYRK1AKDM4E | |
| SCHEMBL4009728 | 0.80 | NPC1 (0.58) | SMN1; SMN2MAPTTP53NPC1RAB9A | |
| SCHEMBL17254809 | 0.79 | MAOB (0.46) | SMN1; SMN2MAPTTP53HDAC6NPC1 | |
| SCHEMBL14878460 | 0.78 | MAPT (0.81) | SMN1; SMN2MAPTTP53NPC1RAB9A | |
| SCHEMBL3042970 | 0.78 | APP (0.70) | SMN1; SMN2MAPTTP53NPC1RAB9A | |
| SCHEMBL11567645 | 0.78 | RAB9A (0.68) | SMN1; SMN2MAPTTP53HDAC6NPC1 | |
| SCHEMBL17254787 | 0.78 | LMNA (0.44) | SMN1; SMN2MAPTTP53HDAC6NPC1 | |
| SCHEMBL12408909 | 0.76 | MAPT (0.84) | SMN1; SMN2MAPTTP53NPC1RAB9A | |
| SCHEMBL17254847 | 0.76 | RORC (0.46) | SMN1; SMN2MAPTTP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306708-B1 | NOVEL BENZOTHIAZOLE AND ANTIRHEUMATIC AGENT COMPRISING IT AS AN ACTIVE INGREDIENT | KANEBO, LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4910211-A | Containing a phenyl substituted in position 2 and an ester in position 4 | KANEBO LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0306708-A1 | Novel benzothiazole and antirheumatic agent comprising it as an active ingredient | KANEBO, LTD. (JP) | 1989-03-15 | — | — | EP | disclosed |