Sugi Predict

Sugi Predict / Compounds / Bithionoloxide

Bithionoloxide

Bithionoloxide

SCHEMBL69373

[O-][S+](c1cc(Cl)cc(Cl)c1O)c1cc(Cl)cc(Cl)c1O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 6/20 0.56
▸ TSHR P16473 5/20 0.56
▸ ALDH1A1 P00352 4/20 0.56
▸ CYP3A4 P08684 2/20 0.56
▸ RECQL P46063 2/20 0.56
▸ HPGD P15428 3/20 0.45
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ TTR P02766 2/20 0.45
▸ THRB P10828 2/20 0.45
▸ MAPK1 P28482 2/20 0.45
▸ ALOX15 P16050 2/20 0.45
▸ ALOX12 P18054 2/20 0.45
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ HIF1A Q16665 2/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ SLC22A2 O15244 1/20 0.45
▸ SLC22A1 O15245 1/20 0.45
▸ NR1I2 O75469 1/20 0.45
▸ SLC22A3 O75751 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12786124 0.89 ALDH1A1 (0.45) HSD17B10TSHRALDH1A1CYP3A4RECQL
Bithionoloxide SCHEMBL11549920 0.83 TSHR (0.40) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL29904878 0.82 TSHR (0.39) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL3337579 0.82 TSHR (0.39) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL29904874 0.79 HSD17B10 (0.40) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL5372785 0.79 HSD17B10 (0.40) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL184648 0.74 HSD17B10 (1.00) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL8872103 0.74 HSD17B10 (1.00) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL20380030 0.72 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL11291920 0.72 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3078664-B1 ANTIPARASITIC DIHYDROAZOLE COMPOSITIONS MERIAL INC (US) 2019-02-20 — — EP claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 — — US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 — — US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 — — CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 — — EP claimed
US-20070225238-A1 Inhibitors of carbonyl reductase for treatment using anthracyclines NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2007-09-27 — — US claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 — — WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 — — US claimed
US-4874388-A Multi-layer delivery system ALZA CORPORATION (US) 1989-10-17 — — US claimed
US-4172118-A Diphenylamine containing therapeutic composition and its applications, particularly in veterinary medicine METABIO (FR) 1979-10-23 — — US claimed
US-12559503-B2 Anthelmintic aza-benzothiophene and aza-benzofuran compounds BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2026-02-24 — — US disclosed
WO-2025202940-A2 ANTIPARASITIC CYCLIC DEPSIPEPTIDES ANIMOL DISCOVERY, INC. (US) 2025-10-02 — — WO disclosed
US-20250268819-A1 DEVICES AND METHODS FOR DELIVERING METHANE INHIBITING COMPOUNDS TO ANIMALS RUMINANT BIOTECH CORP LTD (NZ) 2025-08-28 — — US disclosed
EP-3525590-B1 PESTICIDAL AND PARASITICIDAL VINYL ISOXAZOLINE COMPOUNDS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-08-20 — — EP disclosed
US-20250243197-A1 Anthelmintic Heterocyclic Compounds BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-07-31 — — US disclosed
EP-0209462-A1 Liquid stable anthelmintic and fungicidal composition based on bithionol sulfoxide SOCIETE NATIONALE ELF AQUITAINE (FR) 1987-01-21 — — EP disclosed
EP-0209462-A1 Liquid stable anthelmintic and fungicidal composition based on bithionol sulfoxide SOCIETE NATIONALE ELF AQUITAINE (FR) 1987-01-21 — — EP disclosed
EP-0164927-A2 Release devices CASTEX PRODUCTS LIMITED (GB) 1985-12-18 — — EP disclosed
US-4172118-A Diphenylamine containing therapeutic composition and its applications, particularly in veterinary medicine METABIO (FR) 1979-10-23 — — US disclosed
US-4172118-A Diphenylamine containing therapeutic composition and its applications, particularly in veterinary medicine METABIO (FR) 1979-10-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243197-A1 Anthelmintic Heterocyclic Compounds PAH, PIGS, SDHA HSD17B10 1021/4885TSHR 3716/4885ALDH1A1 209/4885
US-12559503-B2 Anthelmintic aza-benzothiophene and aza-benzofuran compounds HDAC5, NR5A2, HRH4 HSD17B10 1503/4885TSHR 804/4885ALDH1A1 723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.