Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578479 | 0.87 | CA12 (0.38) | LMNANPC1MAPTRAB9AATM | |
| SCHEMBL9622133 | 0.82 | THRB (0.41) | NPC1MAPTRAB9AATMMAOA | |
| SCHEMBL146203 | 0.81 | ADORA3 (0.41) | LMNANPC1RAB9AXBP1HTT | |
| SCHEMBL8412982 | 0.80 | NPC1 (0.38) | NPC1MAPTRAB9AHTTADORA2A | |
| SCHEMBL4284556 | 0.78 | FFAR1 (0.46) | LMNAMAPTGRK6POLBKDM4E | |
| SCHEMBL17145189 | 0.78 | HPGD (0.36) | LMNANPC1RAB9AATMHTT | |
| SCHEMBL10435350 | 0.78 | KDM4E (0.35) | LMNANPC1RAB9AHTTSLC6A4 | |
| SCHEMBL353401 | 0.78 | L3MBTL1 (0.49) | LMNANPC1MAPTRAB9AL3MBTL1 | |
| SCHEMBL2832962 | 0.77 | TP53 (0.43) | LMNANPC1MAPTRAB9APOLB | |
| SCHEMBL13528066 | 0.77 | LMNA (0.30) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271195-B1 | SUBSTITUTED TRIAZINE DERIVATIVES | Horsell Plc (GB) | 1992-04-22 | — | — | EP | claimed |
| US-4912218-A | Substituted triazine derivatives | COOKSON GROUP PLC (GB) | 1990-03-27 | — | — | US | claimed |
| EP-0319296-A2 | Photopolymerisable composition | Horsell Plc (GB) | 1989-06-07 | — | — | EP | claimed |
| EP-0271195-B1 | SUBSTITUTED TRIAZINE DERIVATIVES | Horsell Plc (GB) | 1992-04-22 | — | — | EP | disclosed |
| EP-0389236-A2 | Photopolymerisable composition | Horsell Plc (GB) | 1990-09-26 | — | — | EP | disclosed |
| US-4912218-A | Substituted triazine derivatives | COOKSON GROUP PLC (GB) | 1990-03-27 | — | — | US | disclosed |
| EP-0319296-A2 | Photopolymerisable composition | Horsell Plc (GB) | 1989-06-07 | — | — | EP | disclosed |
| EP-0271195-A1 | Substituted triazine derivatives | Horsell Plc (GB) | 1988-06-15 | — | — | EP | disclosed |