SCHEMBL146203

SCHEMBL146203

CSc1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 2/20 0.41
LMNA P02545 4/20 0.38
NPC1 O15118 4/20 0.38
RAB9A P51151 4/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
PTGS2 P35354 5/20 0.35
NISCH Q9Y2I1 1/20 0.35
HTT P42858 2/20 0.35
CYP1A2 P05177 1/20 0.35
PTBP1 P26599 1/20 0.35
CYP2C19 P33261 1/20 0.35
TNFSF10 P50591 1/20 0.35
KDM1A O60341 1/20 0.35
CNR2 P34972 1/20 0.33
PTGS1 P23219 2/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALDH1A3 P47895 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8412982 0.84 NPC1 (0.38) ADORA3NPC1RAB9ATSHRHTT
SCHEMBL9622217 0.83 ADORA3 (0.42) ADORA3LMNANPC1RAB9ATSHR
SCHEMBL10435350 0.82 KDM4E (0.35) LMNANPC1RAB9AHTTCYP1A2
SCHEMBL13578691 0.81 XDH (0.38) ADORA3LMNATSHRMAPK1CYP1A2
SCHEMBL9622156 0.81 LMNA (0.37) LMNANPC1RAB9AMAPK1PTGS2
SCHEMBL13528066 0.81 LMNA (0.30) LMNA
SCHEMBL1130756 0.80 IDO1 (0.42) NPC1RAB9APTGS2HTTCYP1A2
SCHEMBL16928514 0.79 HRH4 (0.50) CYP1A2CYP2C19SMN1; SMN2
SCHEMBL9622211 0.79 ABCG2 (0.42) LMNAHTTCYP1A2CYP2C19SMN1; SMN2
SCHEMBL22129836 0.79 NPC1 (0.41) ADORA3LMNANPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1539492-B1 HIGH SPEED NEGATIVE-WORKING THERMAL PRINTING PLATES KODAK POLYCHROME GRAPHICS LLC (US) 2006-05-17 EP claimed
EP-1539492-A1 HIGH SPEED NEGATIVE-WORKING THERMAL PRINTING PLATES Kodak Polychrome Graphics, LLC (US) 2005-06-15 EP claimed
US-6893797-B2 High speed negative-working thermal printing plates KODAK POLYCHROME GRAPHICS LLC (US) 2005-05-17 US claimed
WO-2004014652-A1 HIGH SPEED NEGATIVE-WORKING THERMAL PRINTING PLATES KODAK POLYCHROME GRAPHICS LLC (US) 2004-02-19 WO claimed
US-20030124460-A1 High speed negative-working thermal printing plates KODAK PHILIPPINES LTD. 2003-07-03 US claimed
US-5496903-A PHOTPOLYMERIZABLE COATING NIPPON PAINT COMPANY, LTD. (JP) 1996-03-05 US claimed
EP-0271195-B1 SUBSTITUTED TRIAZINE DERIVATIVES Horsell Plc (GB) 1992-04-22 EP claimed
US-4912218-A Substituted triazine derivatives COOKSON GROUP PLC (GB) 1990-03-27 US claimed
EP-0319296-A2 Photopolymerisable composition Horsell Plc (GB) 1989-06-07 EP claimed
EP-0271195-A1 Substituted triazine derivatives Horsell Plc (GB) 1988-06-15 EP claimed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
US-12478562-B2 Dental restoration material composition KURARAY NORITAKE DENTAL INC. (JP) 2025-11-25 US disclosed
US-12465559-B2 Fluorescent curable dental composition and cured product thereof KURARAY NORITAKE DENTAL INC. (JP) 2025-11-11 US disclosed
US-20250213434-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
US-20250207005-A1 ADHESIVE COMPOSITION FOR STEREOLITHOGRAPHIC ARTICLE AND NON-STEREOLITHOGRAPHIC ARTICLE KURARAY NORITAKE DENTAL INC. (JP) 2025-06-26 US disclosed
EP-0271195-B1 SUBSTITUTED TRIAZINE DERIVATIVES Horsell Plc (GB) 1992-04-22 EP disclosed
EP-0389236-A2 Photopolymerisable composition Horsell Plc (GB) 1990-09-26 EP disclosed
US-4912218-A Substituted triazine derivatives COOKSON GROUP PLC (GB) 1990-03-27 US disclosed
EP-0319296-A2 Photopolymerisable composition Horsell Plc (GB) 1989-06-07 EP disclosed
EP-0271195-A1 Substituted triazine derivatives Horsell Plc (GB) 1988-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12465559-B2 Fluorescent curable dental composition and cured product thereof BRD1, TBCA, BAZ1A ADORA3 2279/4885LMNA 133/4885NPC1 4490/4885
US-20250207005-A1 ADHESIVE COMPOSITION FOR STEREOLITHOGRAPHIC ARTICLE AND NON-STEREOLITHOGRAPHIC ARTICLE ACR, CAD, ALG3 ADORA3 1395/4885LMNA 2804/4885NPC1 4792/4885
US-12478562-B2 Dental restoration material composition CAD, MAT2B, RER1 ADORA3 692/4885LMNA 2860/4885NPC1 3973/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL ADORA3 1530/4885LMNA 2975/4885NPC1 3095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.