Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 3/20 | 0.32 |
| ▸ | ADH1C | P00326 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269152 | 0.76 | DPP4 (0.33) | CTSKCTSBCTSSALDH1A1MEN1 | |
| SCHEMBL1685454 | 0.75 | ADH1A (0.40) | ALDH1A1ADH1AADH1C | |
| SCHEMBL1685459 | 0.73 | ADH1A (0.41) | ALDH1A1ADH1AADH1C | |
| SCHEMBL14219531 | 0.71 | ADH1A (0.39) | ALDH1A1HSD17B10ADH1AADH1C | |
| SCHEMBL28334919 | 0.67 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL20774200 | 0.65 | NAAA (0.46) | — | |
| SCHEMBL3363095 | 0.65 | KDM4E (0.43) | CTSKALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL151279 | 0.64 | HRH4 (0.39) | ALDH1A1MEN1USP2POLBALOX15 | |
| SCHEMBL4371656 | 0.63 | ADH1C (0.38) | CTSKCTSBADH1AADH1CDPP4 | |
| SCHEMBL21533309 | 0.62 | ADH1B (0.45) | CTSKCTSBCTSSALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166166-A | Hypotensive agents or treatment of cardiovascular disorders | CASSELLA AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| EP-0471232-A1 | 3-Dicyclohexylamino-sydnonimines, method for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1992-02-19 | — | — | EP | disclosed |