Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | CCR9 | P51686 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536869 | 0.86 | CCR2 (0.76) | CCR2ALDH1A1POLBPTGS2MAPT | |
| SCHEMBL6867612 | 0.82 | CCR2 (0.61) | CCR2ALDH1A1POLBHTTPTGS2 | |
| SCHEMBL9622481 | 0.81 | NOD2 (0.64) | CCR2ALDH1A1POLBPTGS2MAPT | |
| SCHEMBL3956751 | 0.79 | CCR2 (0.84) | CCR2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL16495087 | 0.78 | CCR2 (0.56) | CCR2ALDH1A1POLBPTGS2MAPT | |
| SCHEMBL10444001 | 0.77 | ALDH1A1 (0.55) | CCR2ALDH1A1POLBHTTGRIK1 | |
| SCHEMBL6821149 | 0.77 | GRIK1 (0.75) | CCR2ALDH1A1POLBHTTGRIK1 | |
| SCHEMBL2156810 | 0.77 | GRIK1 (0.56) | CCR2ALDH1A1POLBHTTGRIK1 | |
| SCHEMBL3967516 | 0.77 | CCR2 (0.73) | CCR2PLA2G2AABCB11PLA2G4A | |
| SCHEMBL3659423 | 0.76 | CCR2 (0.63) | CCR2PTGS2MAPTPLA2G2APLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |