Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623564 | 0.90 | SMPD1 (0.36) | KDM4EALDH1A1MAPTHCN4 | |
| SCHEMBL9625718 | 0.90 | KDM4E (0.32) | KDM4EALDH1A1GAAMAPTHCN4 | |
| SCHEMBL9624973 | 0.88 | HCN4 (0.41) | MAPTHCN4 | |
| SCHEMBL9624299 | 0.86 | ITGB3 (0.34) | KDM4EALDH1A1GAAMAPT | |
| SCHEMBL9625186 | 0.84 | SMPD1 (0.34) | MAPTHCN4 | |
| SCHEMBL9624641 | 0.84 | MTNR1A (0.39) | KDM4EALDH1A1MAPTHCN4 | |
| SCHEMBL9623739 | 0.82 | CYP2A6 (0.35) | MAPTHCN4 | |
| SCHEMBL9624301 | 0.81 | MAPT (0.35) | MAPTHCN4 | |
| SCHEMBL9624076 | 0.81 | PRKCB (0.33) | MAPT | |
| SCHEMBL9624436 | 0.80 | PRKCB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116986-A | HETEROAROMATIC AMINE DERIVATIVES | DR. KARL THOMAE GMBH (DE) | 1992-05-26 | — | — | US | disclosed |
| US-4912115-A | Cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1990-03-27 | — | — | US | disclosed |