Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626626 | 0.76 | PDE3B (0.33) | MTNR1APDE3BPDE3AKDM4EALOX15 | |
| SCHEMBL9096470 | 0.71 | HPGD (0.50) | PDE3BPDE3AKDM4EALDH1A1MAPT | |
| SCHEMBL9626996 | 0.67 | KDM4E (0.50) | PDE3BPDE3AKDM4EALDH1A1GAA | |
| SCHEMBL9096832 | 0.65 | PDE3B (0.38) | PDE3BPDE3AMAPKAPK2KDM4EALDH1A1 | |
| SCHEMBL9628449 | 0.64 | HTR2A (0.41) | HTR1AHTR2AHTR2CHTR2BPDE3B | |
| SCHEMBL9095629 | 0.63 | PDE3B (0.34) | PDE3BPDE3AMAPKAPK2ALDH1A1CYP1A2 | |
| SCHEMBL9097597 | 0.62 | PDE3B (0.33) | PDE3BPDE3AHPGD | |
| SCHEMBL5583694 | 0.61 | HTR1A (0.41) | HTR1AMTNR1AKDM4ECYP1A2MAPT | |
| SCHEMBL9626856 | 0.61 | HPGD (0.50) | PDE3BPDE3AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL472541 | 0.60 | DRD2 (0.36) | HTR1ADRD2HTR2AHTR2CMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7173163-A | — | — | None | — | — | JP | disclosed |
| JP-H07173163-A | PYRANO(F)QUINOLINE DERIVATIE AND PHARMACEUTICAL COMPOSITION CONTAINING THE COMPOUND AS ACTIVE COMPOENT | KODAMA KK | 1995-07-11 | — | — | JP | disclosed |