SCHEMBL9627

SCHEMBL9627

Cc1c(F)cccc1B(O)O

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.39
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
ENPP2 Q13822 1/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
HDAC4 P56524 1/20 0.35
ERN1 O75460 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28832409 0.81 ACHE (0.39) ACHEALDH1A1GAAESR1ESR2
SCHEMBL29604796 0.78 CA2 (0.33)
SCHEMBL29399046 0.78 CES2 (0.43) ACHEENPP2CES2CES1ERN1
SCHEMBL6588524 0.78 CA2 (0.33)
SCHEMBL4384 0.78 CES2 (0.43) ACHEENPP2CES2CES1ERN1
SCHEMBL29468967 0.77 ENPP2 (0.46) ACHEGAAENPP2CES2CES1
SCHEMBL115327 0.77 ENPP2 (0.46) ACHEGAAENPP2CES2CES1
Hydrochloric Acid SCHEMBL29017070 0.76 CES2 (0.41) ACHEENPP2CES2CES1ERN1
SCHEMBL2821248 0.76 ERN1 (0.48) ACHEALDH1A1ENPP2CES2CES1
SCHEMBL7772644 0.76 ERN1 (0.48) ACHEALDH1A1ENPP2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-117024342-B Synthesis method of phenanthridine OLED material 上海海皋科技有限公司 2024-11-08 CN claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-20230363426-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-16 US claimed
CN-117024342-A Synthesis method of phenanthridine OLED material 上海海皋科技有限公司 2023-11-10 CN claimed
US-11793220-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2023-10-24 US claimed
US-20220264914-A1 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. 2022-08-25 US claimed
WO-2022159439-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2022-07-28 WO claimed
US-20220225647-A1 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. 2022-07-21 US claimed
US-20220225646-A1 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. 2022-07-21 US claimed
EP-2059227-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY Aeris Therapeutics, Inc. (US) 2009-05-20 EP claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed
US-12630566-B2 KRas G12D inhibitors Mirati Therapeutics, Inc. (US) 2026-05-19 US disclosed
US-20260053393-A1 NEAR-IR GLUCOSE SENSORS PROFUSA INC (US) 2026-02-26 US disclosed
US-12534461-B2 Imidazopyridinyl compounds and use thereof for treatment of neurodegenerative disorders 1ST Biotherapeutics, Inc. (KR) 2026-01-27 US disclosed
EP-1511747-A1 IMIDAZO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LTD. (GB) 2005-03-09 EP disclosed
WO-2005002577-A1 DUAL NK1/NK3 ANTAGONISTS FOR TREATING SCHIZOPHRENIA F. HOFFMANN-LA ROCHE AG (CH) 2005-01-13 WO disclosed
WO-2003099816-A1 IMIDAZO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LIMITED (GB) 2003-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534461-B2 Imidazopyridinyl compounds and use thereof for treatment of neurodegenerative disorders SNCA, HCRTR2, HTT ACHE 322/4885ALDH1A1 1329/4885GAA 1697/4885
US-20260053393-A1 NEAR-IR GLUCOSE SENSORS INSR, IRS1, SLC2A4 ACHE 3703/4885ALDH1A1 3198/4885GAA 2580/4885
US-12630566-B2 KRas G12D inhibitors KRAS, NRAS, HRAS ACHE 4802/4885ALDH1A1 1816/4885GAA 2089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.