SCHEMBL9627765

SCHEMBL9627765

NC(=O)NOc1cccc(Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OGG1 O15527 1/20 0.51
WDR5 P61964 1/20 0.49
PARP1 P09874 1/20 0.48
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
POLB P06746 1/20 0.43
LMNA P02545 2/20 0.43
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
ICAM1 P05362 1/20 0.43
SELE P16581 1/20 0.43
VCAM1 P19320 1/20 0.43
HTR3E A5X5Y0 1/20 0.42
HTR3B O95264 1/20 0.42
HTR3A P46098 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8495864 0.80 OGG1 (0.50) OGG1WDR5MEN1KMT2ASMN1; SMN2
SCHEMBL4344418 0.77 MEN1 (0.73) OGG1WDR5PARP1MEN1KMT2A
SCHEMBL7842555 0.76 OGG1 (0.46) OGG1WDR5KMT2AALDH1A1MAPT
SCHEMBL3646258 0.76 MEN1 (0.52) PARP1MEN1KMT2APOLBALDH1A1
SCHEMBL28441708 0.74 OGG1 (0.48) OGG1KMT2ARXRARXRBRXRG
SCHEMBL23716111 0.74 OGG1 (0.45) OGG1WDR5PARP1
SCHEMBL19513497 0.74 DRD2 (0.56) WDR5KMT2ASMN1; SMN2LMNAHTT
SCHEMBL23715916 0.73 OGG1 (0.44) OGG1WDR5ALDH1A1MAPT
SCHEMBL23716193 0.73 OGG1 (0.44) OGG1WDR5PARP1KMT2APOLB
SCHEMBL9205693 0.73 WDR5 (0.70) WDR5POLBLMNARXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0270683-B1 ARYLOXYUREAS, PROCESS FOR THEIR PREPARATION, AND THEIR USE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-09-09 EP disclosed
US-5112385-A Useful in rice paddies KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-05-12 US disclosed
EP-0268688-B1 SUBSTITUTED ARYLOXYUREAS, PROCESS FOR THEIR PREPARATION, AND THEIR USE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-03-04 EP disclosed
US-4968341-A PRE-AND POSTEMERGENCE HERBICIDES KUMIAI CHEMICAL INDUSTRY CO. (JP) 1990-11-06 US disclosed
EP-0183174-B1 SUBSTITUTED PHENOXY UREA, PROCESSES FOR ITS PREPARATION AND HERBICIDE CONTAINING IT AS ACTIVE INGREDIENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-10-26 EP disclosed
EP-0270683-A1 ARYLOXYUREAS, PROCESS FOR THEIR PREPARATION, AND THEIR USE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-06-15 EP disclosed
EP-0268688-A1 SUBSTITUTED ARYLOXYUREAS, PROCESS FOR THEIR PREPARATION, AND THEIR USE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-06-01 EP disclosed
EP-0183174-A2 Substituted phenoxy urea, processes for its preparation and herbicide containing it as active ingredient KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1986-06-04 EP disclosed