Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23715916 | 0.93 | OGG1 (0.44) | OGG1WDR5SLC6A4TRPM8FNTA | |
| SCHEMBL23716193 | 0.90 | OGG1 (0.44) | OGG1WDR5PARP1 | |
| SCHEMBL23716127 | 0.80 | OGG1 (0.35) | OGG1SYKWDR5SLC6A4RPS6KB1 | |
| SCHEMBL23716135 | 0.79 | KMT2A (0.37) | SYKPARP1 | |
| SCHEMBL23715793 | 0.77 | SYK (0.45) | SYKPARP1FNTAFNTB | |
| SCHEMBL23716180 | 0.76 | S1PR3 (0.44) | OGG1SYKTRPM8 | |
| SCHEMBL13710935 | 0.76 | ROCK2 (0.48) | OGG1SYKTRPM8PARP1 | |
| SCHEMBL23716154 | 0.76 | ROCK2 (0.48) | OGG1SYKTRPM8PARP1 | |
| SCHEMBL23715829 | 0.74 | S1PR3 (0.44) | — | |
| SCHEMBL23716330 | 0.74 | MDM2 (0.38) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |