Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.56 |
| ▸ | NQO2 | P16083 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL136496 | 0.88 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL9628106 | 0.79 | PPARD (0.56) | — | |
| SCHEMBL5263981 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL135119 | 0.79 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL24090506 | 0.79 | HTR2B (0.55) | MTNR1A | |
| SCHEMBL9628948 | 0.79 | HTR1A (0.55) | MTNR1A | |
| SCHEMBL3652699 | 0.78 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL10689067 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL132847 | 0.78 | MTNR1A (0.66) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL10689060 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281261-B1 | 3-AMINOMETHYL DERIVATIVES OF INDANE, INDOLINE AND DIHYDROBENZOFURANE AND DIHYDROBENZOTHIOPHENE | H. LUNDBECK A/S (DK) | 1992-05-06 | — | — | EP | disclosed |
| US-4946863-A | CNS-affecting 6-oxy-3-aminomethyl indanes, compositions thereof, and method of treating therewith | H. LUNDBECK A/S (DK) | 1990-08-07 | — | — | US | disclosed |
| US-4847254-A | CNS affecting 5-oxy-3-aminomethyl-dihydro-benzofurans and benzothiophenes | H. LUNDBECK A/S (DK) | 1989-07-11 | — | — | US | disclosed |