Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10601711 | 0.83 | OPRM1 (0.60) | ALDH1A1LMNAHRH2HRH1HTT | |
| SCHEMBL4693977 | 0.81 | TSHR (0.57) | ALDH1A1LMNAKMT2ACYP2C19L3MBTL1 | |
| SCHEMBL9047536 | 0.80 | ALDH1A1 (0.58) | ALDH1A1LMNAHRH2HRH1HTT | |
| SCHEMBL5492164 | 0.78 | TSHR (0.51) | ALDH1A1LMNAKMT2AL3MBTL1GAA | |
| Carbamic Acid SCHEMBL4082824 | 0.77 | TSHR (0.53) | ALDH1A1LMNAKMT2ACYP2C19L3MBTL1 | |
| SCHEMBL5496259 | 0.77 | OPRM1 (0.52) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL31023851 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNAKMT2ACYP2C19MAPT | |
| SCHEMBL11319497 | 0.74 | CYP2C19 (0.55) | ALDH1A1LMNAHRH2HRH1MEN1 | |
| SCHEMBL9872456 | 0.73 | HSD11B1 (0.60) | ALDH1A1LMNAHRH2HRH1HTT | |
| SCHEMBL9816191 | 0.73 | DRD2 (0.46) | ALDH1A1LMNACYP2C19MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079249-A | Serotine antagonists at 5-HT2 level, antiallergens, antihistamines | ADIR ET COMPAGNIE (FR) | 1992-01-07 | — | — | US | disclosed |
| US-5071847-A | BIS (ARYL) ALKENE COMPOUNDS OF HOMOPIPERIDINES USEFUL AS SEROTONIN-ANTAGONISTS | ADIR ET COMPAGNIE (FR) | 1991-12-10 | — | — | US | disclosed |
| US-5028607-A | Antiserotonine agents | ADIR ET COMPAGNIE (FR) | 1991-07-02 | — | — | US | disclosed |