Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632061 | 0.77 | OPRD1 (0.50) | DRD2DRD4HTR2AHTR2CHTR2B | |
| SCHEMBL16481505 | 0.76 | OPRD1 (0.54) | DRD2DRD4HTR2AHTR2CHTR2B | |
| SCHEMBL4693977 | 0.74 | TSHR (0.57) | OPRD1OPRK1KDM4EALDH1A1LMNA | |
| SCHEMBL5496259 | 0.73 | OPRM1 (0.52) | DRD2DRD4HTR2AHTR2CHTR2B | |
| SCHEMBL9632474 | 0.73 | ALDH1A1 (0.49) | KDM4EALDH1A1LMNAMAPTTSHR | |
| SCHEMBL9630285 | 0.73 | OPRM1 (0.44) | DRD2DRD4HTR2AHTR2COPRD1 | |
| SCHEMBL10601711 | 0.72 | OPRM1 (0.60) | DRD2DRD4HTR2AHTR2CHTR2B | |
| SCHEMBL11643619 | 0.72 | POLB (0.43) | TSHRRAD52 | |
| SCHEMBL5492164 | 0.72 | TSHR (0.51) | OPRD1OPRK1KDM4EALDH1A1LMNA | |
| SCHEMBL9632594 | 0.71 | OPRD1 (0.41) | DRD2DRD4HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3133956-A | — | — | None | — | — | JP | disclosed |
| JP-H03133956-A | PIPERIDINE DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1991-06-07 | — | — | JP | disclosed |