Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633499 | 0.85 | EPHX2 (0.42) | EPHX2LMNAMEN1FAAHMAPK1 | |
| SCHEMBL9633446 | 0.77 | FAAH (0.53) | EPHX2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL9633089 | 0.73 | PAOX (0.42) | CES2LMNA | |
| SCHEMBL9633084 | 0.72 | LMNA (0.36) | EPHX2LMNAMEN1FAAHMAPK1 | |
| SCHEMBL25836455 | 0.71 | EPHX2 (0.56) | EPHX2CES2LMNAMEN1FAAH | |
| SCHEMBL19687365 | 0.71 | CASP2 (0.62) | EPHX2FAAH | |
| SCHEMBL17624918 | 0.69 | CASP2 (0.59) | EPHX2FAAHTSHR | |
| SCHEMBL31060424 | 0.69 | PLA2G2A (0.67) | EPHX2CES2 | |
| Arachidic Acid SCHEMBL28744356 | 0.69 | GPR84 (0.53) | EPHX2MEN1KMT2ATSHR | |
| SCHEMBL8345106 | 0.69 | USP2 (0.51) | EPHX2CES2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |