Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.37 |
| ▸ | ESR1 | P03372 | 7/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
| ▸ | ESRRA | P11474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739115 | 0.87 | MMP3 (0.42) | MMP3CA12CA2CA3CA6 | |
| SCHEMBL1978737 | 0.82 | APP (0.41) | MMP3CA12CA2CA9 | |
| SCHEMBL9219029 | 0.82 | MMP3 (0.52) | MMP3CA12CA2CA3CA6 | |
| SCHEMBL15818998 | 0.82 | MAOA (0.39) | — | |
| SCHEMBL7194431 | 0.82 | ALDH1A1 (0.47) | AR | |
| SCHEMBL7526479 | 0.81 | TSHR (0.43) | CYP19A1XDHSLC22A12 | |
| SCHEMBL15819482 | 0.79 | MAPT (0.44) | CA2 | |
| SCHEMBL10352968 | 0.78 | EGFR (0.36) | — | |
| SCHEMBL8530661 | 0.78 | THRB (0.41) | AR | |
| SCHEMBL3125580 | 0.77 | ESR1 (0.44) | MMP3CA12CA2CA3CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0166509-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-13 | — | — | EP | claimed |