SCHEMBL9634347

SCHEMBL9634347

CCCOC(=O)NCCOc1ccc(Oc2ccc(F)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.51
MAPT P10636 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
LMNA P02545 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
LTA4H P09960 2/20 0.48
ALDH1A1 P00352 2/20 0.47
RAB9A P51151 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
PTPN7 P35236 1/20 0.45
DUSP3 P51452 1/20 0.45
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
ACACB O00763 1/20 0.44
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9634358 0.93 FAAH (0.56) FAAHMAPTL3MBTL1LMNASMN1; SMN2
SCHEMBL9632354 0.90 MAPT (0.51) FAAHMAPTL3MBTL1LMNASMN1; SMN2
SCHEMBL9634003 0.86 MTNR1A (0.53) FAAHMAPTL3MBTL1LMNASMN1; SMN2
SCHEMBL10876260 0.83 MEN1 (0.54) FAAHMAPTL3MBTL1LMNASMN1; SMN2
SCHEMBL7191257 0.82 L3MBTL1 (0.48) FAAHMAPTL3MBTL1LMNASMN1; SMN2
SCHEMBL9633817 0.81 SMN1; SMN2 (0.48) FAAHMAPTL3MBTL1LMNASMN1; SMN2
SCHEMBL9668206 0.80 FAAH (0.55) FAAHMAPTL3MBTL1LMNASMN1; SMN2
SCHEMBL9632340 0.80 LTA4H (0.55) MAPTL3MBTL1LMNASMN1; SMN2LTA4H
SCHEMBL11309905 0.79 NPC1 (0.60) MAPTL3MBTL1LMNASMN1; SMN2ALDH1A1
SCHEMBL10926665 0.79 MAPT (0.48) MAPTL3MBTL1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5114968-A Ovicides, pesticides CIBA-GEIGY CORPORATION (US) 1992-05-19 US disclosed