SCHEMBL9634358

SCHEMBL9634358

CCCCOC(=O)NCCOc1ccc(Oc2ccc(F)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.56
LTA4H P09960 2/20 0.50
MAPT P10636 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
TSHR P16473 1/20 0.48
ACHE P22303 7/20 0.48
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9634347 0.93 FAAH (0.51) FAAHLTA4HMAPTL3MBTL1LMNA
SCHEMBL9632354 0.89 MAPT (0.51) FAAHLTA4HMAPTL3MBTL1LMNA
SCHEMBL9634003 0.85 MTNR1A (0.53) FAAHLTA4HMAPTL3MBTL1TSHR
SCHEMBL7194383 0.85 LTA4H (0.65) LTA4HMAPTL3MBTL1TSHRACHE
SCHEMBL10876260 0.82 MEN1 (0.54) FAAHLTA4HMAPTL3MBTL1TSHR
SCHEMBL5962440 0.81 LMNA (0.55) FAAHMAPTL3MBTL1ACHELMNA
SCHEMBL7191257 0.81 L3MBTL1 (0.48) FAAHLTA4HMAPTL3MBTL1TSHR
SCHEMBL9633817 0.80 SMN1; SMN2 (0.48) FAAHLTA4HMAPTL3MBTL1TSHR
SCHEMBL7201443 0.80 NR5A1 (0.65) LTA4HMAPTL3MBTL1TSHRACHE
SCHEMBL16246082 0.80 ACHE (0.55) MAPTL3MBTL1TSHRACHELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5114968-A Ovicides, pesticides CIBA-GEIGY CORPORATION (US) 1992-05-19 US disclosed