Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635109 | 0.81 | PPARG (0.36) | PPARGPPARDITGB3ITGA2BPPARA | |
| SCHEMBL26312618 | 0.81 | HRH3 (0.40) | THRBHRH3 | |
| SCHEMBL26312614 | 0.81 | HRH3 (0.37) | THRBHRH3 | |
| SCHEMBL419937 | 0.80 | THRB (0.41) | THRB | |
| SCHEMBL1506190 | 0.79 | LTA4H (0.47) | CYP1A2CYP2D6CYP2C19HRH3 | |
| SCHEMBL21610572 | 0.78 | KMT2A (0.47) | — | |
| SCHEMBL5607785 | 0.76 | ALDH1A1 (0.53) | PPARGPPARDPPARATHRB | |
| SCHEMBL7719874 | 0.76 | LMNA (0.53) | HRH3 | |
| SCHEMBL13888322 | 0.76 | KEAP1 (0.51) | — | |
| SCHEMBL9179345 | 0.76 | HRH3 (0.45) | PPARGPPARATHRBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102966-A | Addition polymerization of unsaturated ethers using an unsaturated alkenyl polyether adduct as initiator and a cation-donating compound | SEKISUI CHEMICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |