Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636760 | 0.79 | GID4 (0.53) | GID4PRCP | |
| SCHEMBL1868516 | 0.73 | GID4 (0.57) | GID4PRCP | |
| SCHEMBL9636773 | 0.73 | GID4 (0.47) | GID4OPRK1 | |
| SCHEMBL330217 | 0.71 | PRCP (0.62) | OPRK1PRCP | |
| SCHEMBL9210176 | 0.70 | GID4 (0.49) | GID4PRCP | |
| SCHEMBL9529244 | 0.70 | HTR2A (0.50) | OPRK1PRCP | |
| SCHEMBL9636740 | 0.68 | OPRK1 (0.49) | GID4OPRK1 | |
| SCHEMBL10513388 | 0.67 | DRD2 (0.48) | — | |
| SCHEMBL9529226 | 0.67 | HTR2A (0.49) | OPRK1PRCP | |
| SCHEMBL31568975 | 0.67 | SLC6A4 (0.44) | PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5109008-A | Analgesics, diuretics, antiischemic agents | GLAXO GROUP LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0366327-A1 | Furo- and thieno[3,2-c]pyridines and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1990-05-02 | — | — | EP | disclosed |