Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 12/20 | 0.49 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636773 | 0.82 | GID4 (0.47) | OPRK1GID4 | |
| SCHEMBL9636750 | 0.78 | OPRK1 (0.51) | OPRK1HRH3BCHEACHE | |
| SCHEMBL8717581 | 0.76 | PRCP (0.50) | — | |
| SCHEMBL8789518 | 0.76 | PRCP (0.50) | — | |
| SCHEMBL9636760 | 0.74 | GID4 (0.53) | GID4 | |
| SCHEMBL9636767 | 0.72 | GID4 (0.40) | OPRK1GID4JAK2JAK1 | |
| SCHEMBL8790382 | 0.69 | OPRM1 (0.49) | — | |
| SCHEMBL9637841 | 0.68 | GID4 (0.49) | OPRK1GID4 | |
| SCHEMBL29877787 | 0.67 | OPRK1 (1.00) | OPRK1 | |
| SCHEMBL9637818 | 0.67 | OPRK1 (1.00) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5109008-A | Analgesics, diuretics, antiischemic agents | GLAXO GROUP LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0366327-A1 | Furo- and thieno[3,2-c]pyridines and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1990-05-02 | — | — | EP | disclosed |