Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636740 | 0.82 | OPRK1 (0.49) | GID4OPRK1 | |
| SCHEMBL9636760 | 0.76 | GID4 (0.53) | GID4CYP19A1TBXAS1 | |
| Hydrochloric Acid SCHEMBL8806705 | 0.75 | LMNA (0.34) | OPRK1OPRM1LMNATAAR1 | |
| SCHEMBL3453173 | 0.73 | OPRM1 (0.56) | OPRM1 | |
| SCHEMBL9637841 | 0.73 | GID4 (0.49) | GID4OPRK1 | |
| SCHEMBL329925 | 0.72 | OPRM1 (0.57) | OPRM1LMNA | |
| SCHEMBL9206816 | 0.72 | GID4 (0.43) | GID4OPRM1TAAR1ADRA2AADRA2B | |
| SCHEMBL330238 | 0.72 | OPRM1 (0.57) | OPRM1LMNA | |
| SCHEMBL329828 | 0.72 | OPRM1 (0.57) | OPRM1LMNA | |
| SCHEMBL9528729 | 0.71 | HTR2A (0.44) | OPRK1OPRM1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5109008-A | Analgesics, diuretics, antiischemic agents | GLAXO GROUP LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0366327-A1 | Furo- and thieno[3,2-c]pyridines and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1990-05-02 | — | — | EP | disclosed |