SCHEMBL9636760

SCHEMBL9636760

OCC1NCCc2occc21

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GID4 Q8IVV7 1/20 0.53
HTR6 P50406 1/20 0.35
ADRB2 P07550 2/20 0.32
PRCP P42785 2/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
SLC22A1 O15245 1/20 0.32
DRD2 P14416 2/20 0.31
DRD4 P21917 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ABL1 P00519 1/20 0.31
ALPL P05186 1/20 0.31
GAA P10253 1/20 0.31
RIN1 Q13671 1/20 0.31
KDM1A O60341 1/20 0.31
CYP19A1 P11511 1/20 0.31
TBXAS1 P24557 1/20 0.31
TBXA2R P21731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9637841 0.79 GID4 (0.49) GID4PRCP
SCHEMBL9636773 0.76 GID4 (0.47) GID4CYP19A1TBXAS1
SCHEMBL9636740 0.74 OPRK1 (0.49) GID4
SCHEMBL3798032 0.68 PRCP (0.65) PRCPSLC22A1GAA
SCHEMBL31569387 0.68 PRCP (0.65) PRCPSLC22A1GAA
SCHEMBL16308969 0.68 PRCP (0.65) PRCPSLC22A1GAA
SCHEMBL4049149 0.68 PRCP (0.65) PRCPSLC22A1GAA
SCHEMBL10737197 0.67 GID4 (0.61) GID4KDM1A
SCHEMBL11355703 0.64 HTR6 (0.52) HTR6PRCPSLC22A1MEN1KMT2A
SCHEMBL1779309 0.63 ADRB2 (0.73) ADRB2ADRB1ADRB3DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5109008-A Analgesics, diuretics, antiischemic agents GLAXO GROUP LIMITED (GB) 1992-04-28 US disclosed