Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639973 | 0.84 | HNF4A (0.40) | HNF4ABCAT2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11599752 | 0.82 | BCAT2 (0.53) | HNF4ABCAT2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9639083 | 0.81 | ALDH1A1 (0.37) | KMT2ATSHRALDH1A1L3MBTL1 | |
| SCHEMBL9639015 | 0.77 | ALDH1A1 (0.40) | HNF4ABCAT2KMT2AMEN1ALDH1A1 | |
| SCHEMBL27809921 | 0.74 | HNF4A (0.63) | HNF4ABCAT2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9639979 | 0.74 | MEN1 (0.35) | BCAT2KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL11602495 | 0.73 | SMN1; SMN2 (0.44) | HNF4ABCAT2SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL29404978 | 0.73 | HNF4A (0.52) | HNF4ABCAT2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL628182 | 0.73 | HNF4A (0.52) | HNF4ABCAT2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11599755 | 0.72 | ACMSD (0.47) | HNF4ABCAT2KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098990-A | Reaction of a dialcohol, a diamine or a diacyl aromatic compound with a bis/trichloromethyl ketone | THE DOW CHEMICAL COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0215543-B1 | A NEW PROCESS FOR MAKING POLYESTERS, POLYAMIDES AND POLYKETONES | THE DOW CHEMICAL COMPANY (US) | 1990-04-11 | — | — | EP | disclosed |
| US-4762909-A | Method for making polyketones | THE DOW CHEMICAL COMPANY (US) | 1988-08-09 | — | — | US | disclosed |
| US-4731484-A | Haloacetyl derivatives of aromatic compounds | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0215543-A1 | A new process for making polyesters, polyamides and polyketones | THE DOW CHEMICAL COMPANY (US) | 1987-03-25 | — | — | EP | disclosed |
| EP-0189266-A2 | Purification of haloacetyl derivatives of aromatic hydrocarbons | THE DOW CHEMICAL COMPANY (US) | 1986-07-30 | — | — | EP | disclosed |