Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599752 | 0.84 | BCAT2 (0.53) | ALDH1A1KMT2ABCAT2MEN1HNF4A | |
| SCHEMBL28742349 | 0.81 | PTPN1 (0.41) | ALDH1A1ALOX15CES2CES1GAA | |
| SCHEMBL12431222 | 0.79 | CES2 (0.60) | ALDH1A1HPGDCES2CES1KMT2A | |
| SCHEMBL7532514 | 0.79 | KDM4E (0.54) | ALDH1A1ALOX15HPGDKMT2ACYP3A4 | |
| SCHEMBL16722809 | 0.78 | ALDH1A1 (0.47) | ALDH1A1ALOX15KMT2AL3MBTL1BCAT2 | |
| SCHEMBL8914360 | 0.77 | HPGD (0.46) | ALDH1A1HPGDL3MBTL1POLBMYC | |
| SCHEMBL7937289 | 0.77 | ALDH1A1 (0.59) | ALDH1A1ALOX15HPGDCES2CES1 | |
| SCHEMBL11649443 | 0.77 | ALDH1A1 (0.38) | ALDH1A1ALOX15HPGDCES2CES1 | |
| SCHEMBL29857544 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HPGDKMT2AL3MBTL1MEN1 | |
| SCHEMBL9639019 | 0.77 | HNF4A (0.47) | ALDH1A1KMT2AL3MBTL1BCAT2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098990-A | Reaction of a dialcohol, a diamine or a diacyl aromatic compound with a bis/trichloromethyl ketone | THE DOW CHEMICAL COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0215543-B1 | A NEW PROCESS FOR MAKING POLYESTERS, POLYAMIDES AND POLYKETONES | THE DOW CHEMICAL COMPANY (US) | 1990-04-11 | — | — | EP | disclosed |
| US-4762909-A | Method for making polyketones | THE DOW CHEMICAL COMPANY (US) | 1988-08-09 | — | — | US | disclosed |
| US-4731484-A | Haloacetyl derivatives of aromatic compounds | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0215543-A1 | A new process for making polyesters, polyamides and polyketones | THE DOW CHEMICAL COMPANY (US) | 1987-03-25 | — | — | EP | disclosed |