SCHEMBL9640944

SCHEMBL9640944

CCC(O)N(C)c1ccc(C(=O)c2ccc(N(C)C(O)CC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.53
HPGD P15428 5/20 0.53
MAPT P10636 3/20 0.53
RAB9A P51151 3/20 0.47
NPC1 O15118 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 3/20 0.39
HDAC1 Q13547 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP2C19 P33261 1/20 0.36
CYP3A4 P08684 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SRD5A2 P31213 2/20 0.36
BDKRB2 P30411 1/20 0.36
MEN1 O00255 1/20 0.36
TP53 P04637 1/20 0.36
KMT2A Q03164 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9640577 0.80 HPGD (0.47) ALDH1A1HPGDMAPTRAB9ANPC1
SCHEMBL6843785 0.79 HPGD (0.59) ALDH1A1HPGDMAPTRAB9ANPC1
SCHEMBL4352146 0.79 ALDH1A1 (0.44) ALDH1A1MAPTRAB9ASMN1; SMN2KDM4E
SCHEMBL6007228 0.76 SLC6A2 (0.49) ALDH1A1LMNAKDM4E
SCHEMBL4358295 0.76 SLC6A2 (0.49) ALDH1A1LMNAKDM4E
SCHEMBL7328519 0.73 CHRM5 (0.46) ALDH1A1HPGDMAPTRAB9ANPC1
SCHEMBL82487 0.72 HPGD (0.61) ALDH1A1HPGDMAPTRAB9ANPC1
SCHEMBL11571910 0.71 ALDH1A1 (0.50) ALDH1A1HPGDMAPTRAB9ANPC1
Michler'S Ketone SCHEMBL36517 0.71 ALDH1A1 (1.00) ALDH1A1HPGDMAPTRAB9ANPC1
SCHEMBL274966 0.71 ALDH1A1 (1.00) ALDH1A1HPGDMAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0331007-B1 LIGHT-SENSITIVE RECORDING MATERIALS FOR THE MANUFACTURE OF SCRATCH-RESISTANT INTAGLIO PRINTING FORMES BASF Aktiengesellschaft (DE) 1992-09-02 EP disclosed
US-4994348-A Light-sensitive recording materials for producing mar-resistant intaglio printing plates BASF AKTIENGESELLSCHAFT (DE) 1991-02-19 US disclosed
EP-0331007-A2 Light-sensitive recording materials for the manufacture of scratch-resistant intaglio printing formes BASF Aktiengesellschaft (DE) 1989-09-06 EP disclosed
US-4550072-A Photosensitive recording materials containing particles for the production of abrasion-resistant gravure printing plates, and the production of gravure printing plates using these recording materials BASF AKTIENGESELLSCHAFT (DE) 1985-10-29 US disclosed
US-4548894-A Photosensitive recording materials for the production of abrasion-resistant and scratch-resistant gravure printing plates comprising particles BASF AKTIENGESELLSCHAFT (DE) 1985-10-22 US disclosed
EP-0000342-B1 PHOTOPOLYMERISABLE BINDERS BASF Aktiengesellschaft (DE) 1981-11-25 EP disclosed
US-4147604-A PRINTING INKS, COATINGS, PRINTING PLATES BASF AKTIENGESELLSCHAFT (DE) 1979-04-03 US disclosed
EP-0000342-A1 Photopolymerisable binders BASF Aktiengesellschaft (DE) 1979-01-24 EP disclosed