SCHEMBL6843785

SCHEMBL6843785

CC(O)N(C)c1ccc(C(=O)c2ccc(N(C)C(C)O)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.59
ALDH1A1 P00352 5/20 0.59
MAPT P10636 5/20 0.59
RAB9A P51151 3/20 0.52
NPC1 O15118 2/20 0.52
LMNA P02545 3/20 0.43
ELANE P08246 2/20 0.41
KDM4E B2RXH2 1/20 0.40
HTT P42858 3/20 0.39
SRD5A2 P31213 2/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
PKM P14618 1/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
KMT2A Q03164 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11571910 0.80 ALDH1A1 (0.50) HPGDALDH1A1MAPTRAB9ANPC1
SCHEMBL9640944 0.79 ALDH1A1 (0.53) HPGDALDH1A1MAPTRAB9ANPC1
SCHEMBL11571930 0.76 HPGD (0.46) HPGDALDH1A1MAPTRAB9ANPC1
SCHEMBL412645 0.76 ALDH1A1 (0.50) ALDH1A1MAPTRAB9ASMN1; SMN2MEN1
Michler'S Ketone SCHEMBL36517 0.75 ALDH1A1 (1.00) HPGDALDH1A1MAPTRAB9ANPC1
SCHEMBL274966 0.75 ALDH1A1 (1.00) HPGDALDH1A1MAPTRAB9ANPC1
SCHEMBL9626013 0.75 HPGD (0.48) HPGDALDH1A1MAPTRAB9ANPC1
SCHEMBL9640951 0.75 ALDH1A1 (0.53) HPGDALDH1A1MAPTRAB9ANPC1
SCHEMBL4201252 0.74 ALDH1A1 (0.52) ALDH1A1MAPTKDM4EMEN1TP53
SCHEMBL2497217 0.74 HPGD (0.58) HPGDALDH1A1MAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6797841-B2 HAVING PHOTOINITIATION ACTIVITY WITH MINIMAL OR NO ADVERSE HAZARDOUS CHARACTERISTICS ALBEMARLE CORPORATION 2004-09-28 US claimed
US-6781015-B2 PHOTOPOLYMERIZATION ALBEMARLE CORPORATION 2004-08-24 US claimed
US-6762323-B2 EXPOSING A FORMUALTION CONTAINING A PIGMENT AND A PHOTOPOLYMERIZABLE COMPOUND HAVING AN ETHYLENICALLY UNSATURATED DOUBLE BOND TO RADIATION IN PRESENCE NON-MUTAGENIC PHOTOINITIATOR ALBEMARLE CORPORATION 2004-07-13 US claimed
US-20030078313-A1 Aminobenzophenones and photopolymerizable compositions including the same ALBEMARLE CORPORATION 2003-04-24 US claimed
US-20030073754-A1 Aminobenzophenones and photopolymerizable compositions including the same ALBEMARLE CORPORATION 2003-04-17 US claimed
US-20030065049-A1 Aminobenzophenones and photopolymerizable compositions including the same ALBEMARLE CORPORATION 2003-04-03 US claimed
US-6479706-B1 Aminobenzophenones and photopolymerizable compositions including the same ALBEMARLE CORPORATION 2002-11-12 US disclosed
EP-0422488-B1 Photopolymerisable mixtures and photosensitive recording elements containing such mixtures BASF AG (DE) 1996-04-03 EP disclosed
EP-0331007-B1 LIGHT-SENSITIVE RECORDING MATERIALS FOR THE MANUFACTURE OF SCRATCH-RESISTANT INTAGLIO PRINTING FORMES BASF Aktiengesellschaft (DE) 1992-09-02 EP disclosed
US-4994348-A Light-sensitive recording materials for producing mar-resistant intaglio printing plates BASF AKTIENGESELLSCHAFT (DE) 1991-02-19 US disclosed
US-4921775-A Elements having layers containing mixtures which can be crosslinked by photopolymerization BASF AKTIENGESELLSCHAFT (DE) 1990-05-01 US disclosed
EP-0331007-A2 Light-sensitive recording materials for the manufacture of scratch-resistant intaglio printing formes BASF Aktiengesellschaft (DE) 1989-09-06 EP disclosed
EP-0143201-B1 PHOTOPOLYMERISABLE BLENDS WITH SPECIAL DIAMINOBENZOPHENONE COMPOUNDS BASF Aktiengesellschaft (DE) 1987-08-12 EP disclosed
EP-0055807-B1 MULTILAYER ELEMENTS FOR THE MANUFACTURE OF PRINTING PLATES AND RELIEF FORMS BASF Aktiengesellschaft (DE) 1985-03-06 EP disclosed
US-4459348-A Multi-layer elements suitable for the production of printing plates and relief plates BASF AKTIENGESELLSCHAFT (DE) 1984-07-10 US disclosed
US-4401749-A Multi-layer elements suitable for the production of printing plates and relief plates, and their production BASF AKTIENGESELLSCHAFT (DE) 1983-08-30 US disclosed
EP-0055807-A2 Multilayer elements for the manufacture of printing plates and relief forms BASF Aktiengesellschaft (DE) 1982-07-14 EP disclosed
EP-0000342-B1 PHOTOPOLYMERISABLE BINDERS BASF Aktiengesellschaft (DE) 1981-11-25 EP disclosed
US-4147604-A PRINTING INKS, COATINGS, PRINTING PLATES BASF AKTIENGESELLSCHAFT (DE) 1979-04-03 US disclosed
EP-0000342-A1 Photopolymerisable binders BASF Aktiengesellschaft (DE) 1979-01-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073754-A1 Aminobenzophenones and photopolymerizable compositions including the same TYR, AASDHPPT, ALAD HPGD 2377/4885ALDH1A1 864/4885MAPT 1534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.