Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.35 |
| ▸ | MC1R | Q01726 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27626874 | 0.76 | LTA4H (0.41) | LTA4HCTSSCTSKCYP1A2 | |
| SCHEMBL27626868 | 0.76 | LTA4H (0.41) | LTA4HCTSSCTSKCYP1A2 | |
| SCHEMBL9753260 | 0.70 | EPHX1 (0.41) | EPHX1CTSBCTSSCTSKPPARG | |
| SCHEMBL9644339 | 0.69 | GABRP (0.42) | LTA4HCYP1A2GABRB1GABRB2ANPEP | |
| SCHEMBL9644585 | 0.69 | GRIK1 (0.45) | CTSBANPEPKIF11 | |
| SCHEMBL9752900 | 0.69 | EPHX1 (0.45) | EPHX1CTSBCTSSCTSKPPARG | |
| SCHEMBL8362256 | 0.68 | GABRB1 (0.52) | CTSBCTSSCTSKGABRB1GABRB2 | |
| SCHEMBL31532287 | 0.67 | HTR2A (0.53) | LTA4HMC4RMC5RCTSBCTSS | |
| SCHEMBL7383107 | 0.67 | HTR2A (0.53) | LTA4HMC4RMC5RCTSBCTSS | |
| SCHEMBL27527031 | 0.66 | GABRB1 (0.42) | CTSBCTSSCTSKCYP1A2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505467-A1 | PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES | Astra Pharmaceuticals Limited (GB) | 1992-09-30 | — | — | EP | disclosed |